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CP-25 inhibits PGE2-induced angiogenesis by down-regulating EP4/AC/cAMP/PKA-mediated GRK2 translocation.
Han, Chen-Chen; Liu, Qian; Zhang, Yu; Li, Yi-Fan; Cui, Dong-Qian; Luo, Ting-Ting; Zhang, Yu-Wen; Wang, Xin-Ming; Wang, Chun; Ma, Yang; Wei, Wei.
Afiliação
  • Han CC; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • Liu Q; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • Zhang Y; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • Li YF; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • Cui DQ; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • Luo TT; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • Zhang YW; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • Wang XM; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • Wang C; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • Ma Y; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
  • Wei W; Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei 230032, China.
Clin Sci (Lond) ; 134(3): 331-347, 2020 02 14.
Article em En | MEDLINE | ID: mdl-31967309
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dinoprostona / Regulação para Baixo / Proteínas Quinases Dependentes de AMP Cíclico / AMP Cíclico / Neovascularização Fisiológica / Monoterpenos / Quinase 2 de Receptor Acoplado a Proteína G / Receptores de Prostaglandina E Subtipo EP4 / Glucosídeos Limite: Animals / Humans Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dinoprostona / Regulação para Baixo / Proteínas Quinases Dependentes de AMP Cíclico / AMP Cíclico / Neovascularização Fisiológica / Monoterpenos / Quinase 2 de Receptor Acoplado a Proteína G / Receptores de Prostaglandina E Subtipo EP4 / Glucosídeos Limite: Animals / Humans Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China