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A synthetic heparinoid blocks Tau aggregate cell uptake and amplification.
Stopschinski, Barbara E; Thomas, Talitha L; Nadji, Sourena; Darvish, Eric; Fan, Linfeng; Holmes, Brandon B; Modi, Anuja R; Finnell, Jordan G; Kashmer, Omar M; Estill-Terpack, Sandi; Mirbaha, Hilda; Luu, Hung S; Diamond, Marc I.
Afiliação
  • Stopschinski BE; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390; Department of Neurology, RWTH University Aachen, 52074 Aachen, Germany.
  • Thomas TL; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
  • Nadji S; PharmaRen Discovery LLC, Berkeley, Missouri 63134-3115.
  • Darvish E; PharmaRen Discovery LLC, Berkeley, Missouri 63134-3115.
  • Fan L; Shanghai Acana Pharmtech Co. Ltd., Berkeley, Missouri 63134-3115.
  • Holmes BB; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390; Department of Neurology, University of California, San Francisco, California 94143.
  • Modi AR; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
  • Finnell JG; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
  • Kashmer OM; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
  • Estill-Terpack S; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
  • Mirbaha H; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
  • Luu HS; Department of Pathology, Children's Health, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
  • Diamond MI; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390. Electronic address: marc.diamond@utsouthwestern.edu.
J Biol Chem ; 295(10): 2974-2983, 2020 03 06.
Article em En | MEDLINE | ID: mdl-31974166
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas tau / Heparina de Baixo Peso Molecular Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas tau / Heparina de Baixo Peso Molecular Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha