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Targeting NAD immunometabolism limits severe graft-versus-host disease and has potent antileukemic activity.
Gerner, Romana R; Macheiner, Sophie; Reider, Simon; Siegmund, Kerstin; Grabherr, Felix; Mayr, Lisa; Texler, Bernhard; Moser, Patrizia; Effenberger, Maria; Schwaighofer, Hubert; Moschen, Alexander R; Kircher, Brigitte; Oberacher, Herbert; Zeiser, Robert; Tilg, Herbert; Nachbaur, David.
Afiliação
  • Gerner RR; Department of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University Innsbruck, Innsbruck, Austria. romana.gerner@i-med.ac.at.
  • Macheiner S; Christian Doppler Laboratory for Mucosal Immunology, Medical University Innsbruck, Innsbruck, Austria. romana.gerner@i-med.ac.at.
  • Reider S; Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California San Diego, 92037, La Jolla, CA, USA. romana.gerner@i-med.ac.at.
  • Siegmund K; Department of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University Innsbruck, Innsbruck, Austria.
  • Grabherr F; Christian Doppler Laboratory for Mucosal Immunology, Medical University Innsbruck, Innsbruck, Austria.
  • Mayr L; Christian Doppler Laboratory for Mucosal Immunology, Medical University Innsbruck, Innsbruck, Austria.
  • Texler B; Department for Pharmacology and Genetics, Medical University Innsbruck, Innsbruck, Austria.
  • Moser P; Department of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University Innsbruck, Innsbruck, Austria.
  • Effenberger M; Department of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University Innsbruck, Innsbruck, Austria.
  • Schwaighofer H; Christian Doppler Laboratory for Mucosal Immunology, Medical University Innsbruck, Innsbruck, Austria.
  • Moschen AR; Department of Pathology, Medical University Innsbruck, Innsbruck, Austria.
  • Kircher B; Department of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University Innsbruck, Innsbruck, Austria.
  • Oberacher H; Department of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University Innsbruck, Innsbruck, Austria.
  • Zeiser R; Department of Internal Medicine I, Gastroenterology, Hepatology & Endocrinology, Medical University Innsbruck, Innsbruck, Austria.
  • Tilg H; Christian Doppler Laboratory for Mucosal Immunology, Medical University Innsbruck, Innsbruck, Austria.
  • Nachbaur D; Department of Internal Medicine V, Hematology & Oncology, Medical University Innsbruck, Innsbruck, Austria.
Leukemia ; 34(7): 1885-1897, 2020 07.
Article em En | MEDLINE | ID: mdl-31974433
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Acrilamidas / Leucemia / Citocinas / Linfócitos T Reguladores / Nicotinamida Fosforribosiltransferase / Doença Enxerto-Hospedeiro / Memória Imunológica / NAD / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Áustria
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Acrilamidas / Leucemia / Citocinas / Linfócitos T Reguladores / Nicotinamida Fosforribosiltransferase / Doença Enxerto-Hospedeiro / Memória Imunológica / NAD / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Áustria