Elucidating the preference of dimeric over monomeric form for thermal stability of Thermus thermophilus isopropylmalate dehydrogenase: A molecular dynamics perspective.

Sharma, Reetu; Sagurthi, Someswar Rao; Narahari Sastry, G

Sharma, Reetu; Sagurthi, Someswar Rao; Narahari Sastry, G.

Afiliação

Sharma R; Centre for Molecular Modeling, Division of Applied Biology, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad, India. Electronic address: sharmar@tech-center.com.
Sagurthi SR; Department of Genetics and Biotechnology, Osmania University, Hyderabad, India.
Narahari Sastry G; Advanced Computation and Data Sciences Division, CSIR-North East Institute of Scientific and Industrial Research, Assam, India. Electronic address: gnsastry@gmail.com.

J Mol Graph Model ; 96: 107530, 2020 05.

Article em En | MEDLINE | ID: mdl-31986322

Assuntos

Simulação de Dinâmica Molecular; Thermus thermophilus; 3-Isopropilmalato Desidrogenase; Oxirredutases do Álcool/metabolismo; Estabilidade Enzimática

Palavras-chave

Dimer; Isopropylmalate dehydrogenase; Molecular dynamics; Monomer; Thermal stability; Thermus thermophilus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Thermus thermophilus / Simulação de Dinâmica Molecular Idioma: En Revista: J Mol Graph Model Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article

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