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Development of a covalent inhibitor of gut bacterial bile salt hydrolases.
Adhikari, Arijit A; Seegar, Tom C M; Ficarro, Scott B; McCurry, Megan D; Ramachandran, Deepti; Yao, Lina; Chaudhari, Snehal N; Ndousse-Fetter, Sula; Banks, Alexander S; Marto, Jarrod A; Blacklow, Stephen C; Devlin, A Sloan.
Afiliação
  • Adhikari AA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Seegar TCM; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Ficarro SB; Department of Cancer Biology, Department of Oncologic Pathology, Blais Proteomics Center, Dana-Farber Cancer Institute, Boston, MA, USA.
  • McCurry MD; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
  • Ramachandran D; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Yao L; Division of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconness Medical Center, Boston, MA, USA.
  • Chaudhari SN; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Ndousse-Fetter S; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Banks AS; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Marto JA; Division of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconness Medical Center, Boston, MA, USA.
  • Blacklow SC; Department of Cancer Biology, Department of Oncologic Pathology, Blais Proteomics Center, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Devlin AS; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Nat Chem Biol ; 16(3): 318-326, 2020 03.
Article em En | MEDLINE | ID: mdl-32042200
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microbioma Gastrointestinal / Amidoidrolases Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microbioma Gastrointestinal / Amidoidrolases Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Chem Biol Assunto da revista: BIOLOGIA / QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos