A case of porphyria cutanea tarda in the setting of hepatitis C infection and tobacco usage.
Dermatol Online J
; 25(12)2019 Dec 15.
Article
em En
| MEDLINE
| ID: mdl-32045169
ABSTRACT
Porphyria cutanea tarda (PCT) is the most common type of porphyria, presenting in middle-aged patients with a photodistributed vesiculobullous eruption, milia, and scars. Porphyria cutanea tarda occurs in relation to inhibition of uroporphyrinogen decarboxylase, a key enzyme in the heme biosynthesis pathway. A number of genetic and acquired factors increase susceptibility to PCT by reducing uroporphyrinogen decarboxylase activity. A handful of other vesiculobullous conditions may mimic PCT both clinically and histologically; therefore, both skin biopsy and laboratory evaluation are helpful in confirming the diagnosis. We report a case of PCT in the setting of cigarette usage and untreated hepatitis C infection.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fumar
/
Hepatite C
/
Porfiria Cutânea Tardia
Tipo de estudo:
Etiology_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Dermatol Online J
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2019
Tipo de documento:
Article