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Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery.
Laidou, Stamatia; Alanis-Lobato, Gregorio; Pribyl, Jan; Raskó, Tamás; Tichy, Boris; Mikulasek, Kamil; Tsagiopoulou, Maria; Oppelt, Jan; Kastrinaki, Georgia; Lefaki, Maria; Singh, Manvendra; Zink, Annika; Chondrogianni, Niki; Psomopoulos, Fotis; Prigione, Alessandro; Ivics, Zoltán; Pospisilova, Sarka; Skladal, Petr; Izsvák, Zsuzsanna; Andrade-Navarro, Miguel A; Petrakis, Spyros.
Afiliação
  • Laidou S; Institute of Applied Biosciences/Centre for Research and Technology Hellas, 57001, Thessaloniki, Greece.
  • Alanis-Lobato G; Faculty of Biology, Johannes Gutenberg University Mainz, 55122, Mainz, Germany; Human Embryo and Stem Cell Laboratory, The Francis Crick Institute, NW1 1AT, London, UK.
  • Pribyl J; Central European Institute of Technology, Masaryk University, 62500, Brno, Czech Republic.
  • Raskó T; Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, 13125, Germany.
  • Tichy B; Central European Institute of Technology, Masaryk University, 62500, Brno, Czech Republic.
  • Mikulasek K; Central European Institute of Technology, Masaryk University, 62500, Brno, Czech Republic; National Centre for Biomolecular Research, Faculty of Science, Masaryk University, 62500, Brno, Czech Republic.
  • Tsagiopoulou M; Institute of Applied Biosciences/Centre for Research and Technology Hellas, 57001, Thessaloniki, Greece.
  • Oppelt J; Central European Institute of Technology, Masaryk University, 62500, Brno, Czech Republic.
  • Kastrinaki G; Aerosol and Particle Technology Laboratory/Chemical Process & Energy Resources Institute/Centre for Research and Technology Hellas, 57001, Thessaloniki, Greece.
  • Lefaki M; Institute of Biology, Medicinal Chemistry & Biotechnology/National Hellenic Research Foundation, 11365, Athens, Greece.
  • Singh M; Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, 13125, Germany.
  • Zink A; Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, 13125, Germany; Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children's Hospital, Heinrich Heine University, 40225, Düsseldorf, Germany.
  • Chondrogianni N; Institute of Biology, Medicinal Chemistry & Biotechnology/National Hellenic Research Foundation, 11365, Athens, Greece.
  • Psomopoulos F; Institute of Applied Biosciences/Centre for Research and Technology Hellas, 57001, Thessaloniki, Greece; Department of Molecular Medicine and Surgery, Karolinska Institutet, 17177, Stockholm, Sweden.
  • Prigione A; Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, 13125, Germany; Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children's Hospital, Heinrich Heine University, 40225, Düsseldorf, Germany.
  • Ivics Z; Division of Medical Biotechnology, Paul-Ehrlich-Institute, 63225, Langen, Germany.
  • Pospisilova S; Central European Institute of Technology, Masaryk University, 62500, Brno, Czech Republic.
  • Skladal P; Central European Institute of Technology, Masaryk University, 62500, Brno, Czech Republic.
  • Izsvák Z; Max-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Berlin, 13125, Germany. Electronic address: zizsvak@mdc-berlin.de.
  • Andrade-Navarro MA; Faculty of Biology, Johannes Gutenberg University Mainz, 55122, Mainz, Germany.
  • Petrakis S; Institute of Applied Biosciences/Centre for Research and Technology Hellas, 57001, Thessaloniki, Greece. Electronic address: spetrak@certh.gr.
Redox Biol ; 32: 101458, 2020 05.
Article em En | MEDLINE | ID: mdl-32145456
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Corpos de Inclusão Intranuclear / Proteínas do Tecido Nervoso Limite: Humans Idioma: En Revista: Redox Biol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Grécia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Corpos de Inclusão Intranuclear / Proteínas do Tecido Nervoso Limite: Humans Idioma: En Revista: Redox Biol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Grécia