Use of Dietary Components to Reduce the Bioaccessibility and Bioavailability of Cadmium in Rice.
J Agric Food Chem
; 68(14): 4166-4175, 2020 Apr 08.
Article
em En
| MEDLINE
| ID: mdl-32189501
ABSTRACT
Reducing Cd bioavailability in the systemic circulation is an alternative strategy to reduce Cd exposure. The influence of 39 dietary components on Cd bioaccessibility in water or rice was determined using an in vitro gastrointestinal model, following which an in vivo bioassay was used to determine the most effective components on Cd bioavailability in rice. The results showed that several components significantly reduced the solubility of Cd (10-98%) in the intestinal phase. Tannic acid, TiO2, zinc gluconate, CaCl2, and proanthocyanidins were the most effective in decreasing Cd bioaccessibility in rice, with reductions of 93-97, 54-61, 32-49, 24-32, and 11-14%, respectively. Upon adding the dietary components, the reduction rates of the Cd-relative bioavailability (Cd-RBA) were 20-58 and 10-31% in the kidneys and the liver, respectively. The results may have important implications for reducing health risks associated with Cd exposure via consumption of rice.
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Texto completo:
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oryza
/
Cádmio
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Contaminação de Alimentos
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Trato Gastrointestinal
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Dieta
Limite:
Animals
Idioma:
En
Revista:
J Agric Food Chem
Ano de publicação:
2020
Tipo de documento:
Article