The multifaceted role of kinases in amyotrophic lateral sclerosis: genetic, pathological and therapeutic implications.

Guo, Wenting; Vandoorne, Tijs; Steyaert, Jolien; Staats, Kim A; Van Den Bosch, Ludo

Guo, Wenting; Vandoorne, Tijs; Steyaert, Jolien; Staats, Kim A; Van Den Bosch, Ludo.

Afiliação

Guo W; KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), Leuven, Belgium.
Vandoorne T; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.
Steyaert J; KU Leuven-Stem Cell Institute (SCIL), Leuven, Belgium.
Staats KA; KU Leuven-University of Leuven, Department of Neurosciences, Experimental Neurology, and Leuven Brain Institute (LBI), Leuven, Belgium.
Van Den Bosch L; VIB, Center for Brain & Disease Research, Laboratory of Neurobiology, Leuven, Belgium.

Brain ; 143(6): 1651-1673, 2020 06 01.

Article em En | MEDLINE | ID: mdl-32206784

Assuntos

Esclerose Lateral Amiotrófica/genética; Esclerose Lateral Amiotrófica/patologia; Esclerose Lateral Amiotrófica/terapia; Feminino; Humanos; Masculino; Neurônios Motores/metabolismo; Neurônios Motores/patologia; Fosforilação; Proteínas Quinases/metabolismo

Palavras-chave

amyotrophic lateral sclerosis; kinase; motor neuron; phosphorylation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Brain Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Bélgica

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google