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The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L.
Hao, Bing-Bing; Li, Xiao-Jing; Jia, Xing-Long; Wang, Yu-Xing; Zhai, Lin-Hui; Li, Duan-Zhuo; Liu, Jie; Zhang, Die; Chen, Yu-Lu; Xu, Yong-Hu; Lee, Sang-Kyu; Xu, Guo-Feng; Chen, Xiao-Hua; Dang, Yong-Jun; Liu, Bin; Tan, Min-Jia.
Afiliação
  • Hao BB; The Chemical Proteomics Center and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Li XJ; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Jia XL; Key Laboratory of Metabolism and Molecular Medicine, The Ministry of Education, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, 200030, China.
  • Wang YX; The Chemical Proteomics Center and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zhai LH; Lab for Noncoding RNA and Cancer, School of Life Science, Shanghai University, Shanghai, 200444, China.
  • Li DZ; Hubei Key Laboratory of Kidney Disease Pathogenesis and Intervention, Hubei Polytechnic University School of Medicine, Huangshi, 435003, China.
  • Liu J; The Chemical Proteomics Center and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zhang D; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Chen YL; Hubei Key Laboratory of Kidney Disease Pathogenesis and Intervention, Hubei Polytechnic University School of Medicine, Huangshi, 435003, China.
  • Xu YH; Hubei Key Laboratory of Kidney Disease Pathogenesis and Intervention, Hubei Polytechnic University School of Medicine, Huangshi, 435003, China.
  • Lee SK; Hubei Key Laboratory of Kidney Disease Pathogenesis and Intervention, Hubei Polytechnic University School of Medicine, Huangshi, 435003, China.
  • Xu GF; Hubei Key Laboratory of Kidney Disease Pathogenesis and Intervention, Hubei Polytechnic University School of Medicine, Huangshi, 435003, China.
  • Chen XH; Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang St., Shanghai, 200092, China.
  • Dang YJ; BK21, Plus KNU Multi-Omics based Creative Drug Research Team, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
  • Liu B; Department of Pediatric Urology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang St., Shanghai, 200092, China.
  • Tan MJ; University of Chinese Academy of Sciences, Beijing, 100049, China.
Acta Pharmacol Sin ; 41(9): 1246-1254, 2020 Sep.
Article em En | MEDLINE | ID: mdl-32210356
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Talidomida / Proteínas Proto-Oncogênicas / Proteínas Supressoras de Tumor / Ubiquitina-Proteína Ligases / Proteínas Adaptadoras de Transdução de Sinal / Mitofagia / Proteínas de Membrana Limite: Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Talidomida / Proteínas Proto-Oncogênicas / Proteínas Supressoras de Tumor / Ubiquitina-Proteína Ligases / Proteínas Adaptadoras de Transdução de Sinal / Mitofagia / Proteínas de Membrana Limite: Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China