E2f8 and Dlg2 genes have independent effects on impaired insulin secretion associated with hyperglycaemia.

Yang, Chieh-Hsin; Mangiafico, Salvatore P; Waibel, Michaela; Loudovaris, Thomas; Loh, Kim; Thomas, Helen E; Morahan, Grant; Andrikopoulos, Sofianos

Yang, Chieh-Hsin; Mangiafico, Salvatore P; Waibel, Michaela; Loudovaris, Thomas; Loh, Kim; Thomas, Helen E; Morahan, Grant; Andrikopoulos, Sofianos.

Afiliação

Yang CH; Department of Medicine (Austin Health), Austin Hospital, University of Melbourne, Level 7, Lance Townsend Building, Studley Road, Heidelberg, VIC, 3084, Australia. jyang@svi.edu.au.
Mangiafico SP; St Vincent's Institute of Medical Research, 9 Princes Street, Fitzroy, VIC, 3065, Australia. jyang@svi.edu.au.
Waibel M; Department of Medicine (Austin Health), Austin Hospital, University of Melbourne, Level 7, Lance Townsend Building, Studley Road, Heidelberg, VIC, 3084, Australia.
Loudovaris T; St Vincent's Institute of Medical Research, 9 Princes Street, Fitzroy, VIC, 3065, Australia.
Loh K; St Vincent's Institute of Medical Research, 9 Princes Street, Fitzroy, VIC, 3065, Australia.
Thomas HE; St Vincent's Institute of Medical Research, 9 Princes Street, Fitzroy, VIC, 3065, Australia.
Morahan G; St Vincent's Institute of Medical Research, 9 Princes Street, Fitzroy, VIC, 3065, Australia.
Andrikopoulos S; Harry Perkins Institute of Medical Research, Nedlands, WA, Australia.

Diabetologia ; 63(7): 1333-1348, 2020 07.

Article em En | MEDLINE | ID: mdl-32356104

Assuntos

Guanilato Quinases/metabolismo; Hiperglicemia/metabolismo; Insulina/metabolismo; Proteínas de Membrana/metabolismo; Proteínas Repressoras/metabolismo; Animais; Glicemia/metabolismo; Linhagem Celular; Feminino; Estudo de Associação Genômica Ampla; Guanilato Quinases/genética; Hiperglicemia/genética; Masculino; Proteínas de Membrana/genética; Camundongos; Proteínas Repressoras/genética

Palavras-chave

Collaborative cross; Diabetes susceptibility; Discs large homologue 2; E2F transcription factor 8; Glucose-stimulated insulin secretion; Hyperglycaemia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Guanilato Quinases / Hiperglicemia / Insulina / Proteínas de Membrana Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Diabetologia Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália

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