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Lipidomics Profiling of Hidradenitis Suppurativa Skin Lesions Reveals Lipoxygenase Pathway Dysregulation and Accumulation of Proinflammatory Leukotriene B4.
Penno, Carlos A; Jäger, Petra; Laguerre, Claire; Hasler, Franziska; Hofmann, Andreas; Gass, Stephanie K; Wettstein-Ling, Barbara; Schaefer, Dirk J; Avrameas, Alexandre; Raulf, Friedrich; Wieczorek, Grazyna; Lehmann, Joachim C U; Loesche, Christian; Roth, Lukas; Röhn, Till A.
Afiliação
  • Penno CA; Analytical Sciences & Imaging, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Jäger P; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Laguerre C; Analytical Sciences & Imaging, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Hasler F; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Hofmann A; Analytical Sciences & Imaging, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Gass SK; Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital, Basel, and University of Basel, Basel, Switzerland.
  • Wettstein-Ling B; Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital, Basel, and University of Basel, Basel, Switzerland.
  • Schaefer DJ; Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital, Basel, and University of Basel, Basel, Switzerland.
  • Avrameas A; Biomarker Development, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Raulf F; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Wieczorek G; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Lehmann JCU; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Loesche C; Translational Medicine, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Roth L; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
  • Röhn TA; Autoimmunity, Transplantation and Inflammation, Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland. Electronic address: till.roehn@novartis.com.
J Invest Dermatol ; 140(12): 2421-2432.e10, 2020 12.
Article em En | MEDLINE | ID: mdl-32387270
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Araquidonato 5-Lipoxigenase / Araquidonato 15-Lipoxigenase / Hidradenite Supurativa / Leucotrieno B4 Tipo de estudo: Observational_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Invest Dermatol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pele / Araquidonato 5-Lipoxigenase / Araquidonato 15-Lipoxigenase / Hidradenite Supurativa / Leucotrieno B4 Tipo de estudo: Observational_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Invest Dermatol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça