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CUDC-907, a novel dual PI3K and HDAC inhibitor, in prostate cancer: Antitumour activity and molecular mechanism of action.
Hu, Cheng; Xia, Hongyan; Bai, Shanshan; Zhao, Jianlei; Edwards, Holly; Li, Xinyu; Yang, Yanrong; Lyu, Jing; Wang, Guan; Zhan, Yang; Dong, Yan; Ge, Yubin.
Afiliação
  • Hu C; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Xia H; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Bai S; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Zhao J; Department of Structural and Cellular Biology, Tulane University School of Medicine, Tulane Cancer Center, New Orleans, LA, USA.
  • Edwards H; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Li X; Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.
  • Yang Y; Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA.
  • Lyu J; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Wang G; School of Nursing, Jilin University, Changchun, China.
  • Zhan Y; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Dong Y; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
  • Ge Y; National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun, China.
J Cell Mol Med ; 24(13): 7239-7253, 2020 07.
Article em En | MEDLINE | ID: mdl-32459381

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Pirimidinas / Morfolinas / Inibidores de Histona Desacetilases / Inibidores de Fosfoinositídeo-3 Quinase / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Revista: J Cell Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Pirimidinas / Morfolinas / Inibidores de Histona Desacetilases / Inibidores de Fosfoinositídeo-3 Quinase / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans / Male Idioma: En Revista: J Cell Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China