Ultrasonic vocalization in rat pups as a marker of behavioral development: an investigation of the effects of drugs influencing brain opioid system.
Neurotoxicol Teratol
; 10(5): 465-9, 1988.
Article
em En
| MEDLINE
| ID: mdl-3247002
ABSTRACT
Early postnatal exposure to morphine significantly influenced the ultrasonic vocalization of rat pups removed from their nest. In particular, a significant decrease in the rate of calling, sound pressure level and range of frequency was found in morphine-treated animals; moreover, the duration of calls was significantly increased by morphine administration. Conversely, neither beta-casomorphins (beta CMS), which are opioid peptides derived from the enzymatic digestion of milk protein (beta-casein), nor an opioid antagonist, like naloxone, significantly affected ultrasonic emission. The results are discussed with particular reference to the role of the opioid system in separation distress-induced vocalization in young animals.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vocalização Animal
/
Envelhecimento
/
Endorfinas
/
Morfina
/
Naloxona
Limite:
Animals
Idioma:
En
Revista:
Neurotoxicol Teratol
Assunto da revista:
NEUROLOGIA
/
TOXICOLOGIA
Ano de publicação:
1988
Tipo de documento:
Article
País de afiliação:
Itália