Characterization of a novel polymeric prodrug of an antibacterial agent synthesized by mechanochemical solid-state polymerization.

Yamauchi, Yukinori; Doi, Naoki; Kondo, Shin-Ichi; Sasai, Yasushi; Kuzuya, Masayuki

Yamauchi, Yukinori; Doi, Naoki; Kondo, Shin-Ichi; Sasai, Yasushi; Kuzuya, Masayuki.

Afiliação

Yamauchi Y; Department of Pharmaceutical Physical Chemistry, College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Ehime, Japan.
Doi N; Laboratory of Pharmaceutical Physical Chemistry, Department of Drug Delivery Technology and Sciences, Gifu Pharmaceutical University, Gifu, Japan.
Kondo SI; Laboratory of Pharmaceutical Physical Chemistry, Department of Drug Delivery Technology and Sciences, Gifu Pharmaceutical University, Gifu, Japan.
Sasai Y; Laboratory of Pharmaceutical Physical Chemistry, Department of Drug Delivery Technology and Sciences, Gifu Pharmaceutical University, Gifu, Japan.
Kuzuya M; Department of Health and Welfare, Faculty of Human Welfare, Chubu Gakuin University, Gifu, Japan.

Drug Dev Res ; 81(7): 867-874, 2020 11.

Article em En | MEDLINE | ID: mdl-32501557

Assuntos

Anidridos/química; Antibacterianos/química; Metacrilatos/química; Ácido Nalidíxico/química; Polímeros/química; Pró-Fármacos/química; Liberação Controlada de Fármacos; Humanos; Hidrólise; Polimerização; Pós

Palavras-chave

acid anhydride bond; antibacterial agent; controlled release; mechanochemical polymerization; polymeric prodrug

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polímeros / Pró-Fármacos / Ácido Nalidíxico / Anidridos / Metacrilatos / Antibacterianos Limite: Humans Idioma: En Revista: Drug Dev Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão

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