Characterization of benzimidazole resistance in Haemonchus contortus: integration of phenotypic, genotypic and proteomic approaches.

Tan, Tiong Kai; Lim, Yvonne A L; Chua, Kek Heng; Chai, Hwa Chia; Low, Van Lun; Bathmanaban, Premaalatha; Affendi, Sarah; Wang, Daryi; Panchadcharam, Chandrawathani

Tan, Tiong Kai; Lim, Yvonne A L; Chua, Kek Heng; Chai, Hwa Chia; Low, Van Lun; Bathmanaban, Premaalatha; Affendi, Sarah; Wang, Daryi; Panchadcharam, Chandrawathani.

Afiliação

Tan TK; Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. stanley.monas@gmail.com.
Lim YAL; Department of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. limailian@um.edu.my.
Chua KH; Centre of Excellence for Research in AIDS (CERIA), University of Malaya, Kuala Lumpur, Malaysia. limailian@um.edu.my.
Chai HC; Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Low VL; Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Bathmanaban P; Tropical Infectious Diseases Research and Education Centre (TIDREC), University of Malaya, Kuala Lumpur, Malaysia.
Affendi S; Veterinary Research Institute, Jalan Sultan Azlan Shah, Ipoh, Perak, Malaysia.
Wang D; Tropical Infectious Diseases Research and Education Centre (TIDREC), University of Malaya, Kuala Lumpur, Malaysia.
Panchadcharam C; Biodiversity Research Center, Academia Sinica, Taipei, Taiwan.

Parasitol Res ; 119(9): 2851-2862, 2020 Sep.

Article em En | MEDLINE | ID: mdl-32651637

Assuntos

Albendazol/farmacologia; Anti-Helmínticos/farmacologia; Benzimidazóis/farmacologia; Resistência a Medicamentos/genética; Haemonchus/efeitos dos fármacos; Animais; Antioxidantes/metabolismo; Cromatografia Líquida; Glutamato Desidrogenase/metabolismo; Hemoncose/tratamento farmacológico; Haemonchus/genética; Reação em Cadeia da Polimerase; Proteômica; Ovinos; Doenças dos Ovinos/parasitologia; Espectrometria de Massas em Tandem; Tubulina (Proteína)/genética

Palavras-chave

2D-DIGE; Benzimidazole; F200Y; FECRT

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzimidazóis / Resistência a Medicamentos / Albendazol / Haemonchus / Anti-Helmínticos Limite: Animals Idioma: En Revista: Parasitol Res Assunto da revista: PARASITOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Malásia

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