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Introduction of Ultra-High-Field MR Imaging in Infants: Preparations and Feasibility.
Annink, K V; van der Aa, N E; Dudink, J; Alderliesten, T; Groenendaal, F; Lequin, M; Jansen, F E; Rhebergen, K S; Luijten, P; Hendrikse, J; Hoogduin, H J M; Huijing, E R; Versteeg, E; Visser, F; Raaijmakers, A J E; Wiegers, E C; Klomp, D W J; Wijnen, J P; Benders, M J N L.
Afiliação
  • Annink KV; From the Departments of Neonatology (K.V.A., N.E.v.d.A., J.D., T.A., F.G., M.J.N.L.B.), and Paediatric Neurology (F.E.J.), University Medical Center Utrecht Brain Center.
  • van der Aa NE; From the Departments of Neonatology (K.V.A., N.E.v.d.A., J.D., T.A., F.G., M.J.N.L.B.), and Paediatric Neurology (F.E.J.), University Medical Center Utrecht Brain Center.
  • Dudink J; From the Departments of Neonatology (K.V.A., N.E.v.d.A., J.D., T.A., F.G., M.J.N.L.B.), and Paediatric Neurology (F.E.J.), University Medical Center Utrecht Brain Center.
  • Alderliesten T; From the Departments of Neonatology (K.V.A., N.E.v.d.A., J.D., T.A., F.G., M.J.N.L.B.), and Paediatric Neurology (F.E.J.), University Medical Center Utrecht Brain Center.
  • Groenendaal F; From the Departments of Neonatology (K.V.A., N.E.v.d.A., J.D., T.A., F.G., M.J.N.L.B.), and Paediatric Neurology (F.E.J.), University Medical Center Utrecht Brain Center.
  • Lequin M; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Jansen FE; From the Departments of Neonatology (K.V.A., N.E.v.d.A., J.D., T.A., F.G., M.J.N.L.B.), and Paediatric Neurology (F.E.J.), University Medical Center Utrecht Brain Center.
  • Rhebergen KS; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Luijten P; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Hendrikse J; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Hoogduin HJM; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Huijing ER; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Versteeg E; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Visser F; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Raaijmakers AJE; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Wiegers EC; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Klomp DWJ; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Wijnen JP; the Departments of Radiology (M.L., P.L., J.H., H.J.M.H., E.R.H., E.V., F.V., A.J.E.R., E.C.W., D.W.J.K., J.P.W.), and Otorhinolaryngology and Head and Neck Surgery (K.S.R.), University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
  • Benders MJNL; From the Departments of Neonatology (K.V.A., N.E.v.d.A., J.D., T.A., F.G., M.J.N.L.B.), and Paediatric Neurology (F.E.J.), University Medical Center Utrecht Brain Center m.benders@umcutrecht.nl.
AJNR Am J Neuroradiol ; 41(8): 1532-1537, 2020 08.
Article em En | MEDLINE | ID: mdl-32732273
ABSTRACT
BACKGROUND AND

PURPOSE:

Cerebral MR imaging in infants is usually performed with a field strength of up to 3T. In adults, a growing number of studies have shown added diagnostic value of 7T MR imaging. 7T MR imaging might be of additional value in infants with unexplained seizures, for example. The aim of this study was to investigate the feasibility of 7T MR imaging in infants. We provide information about the safety preparations and show the first MR images of infants at 7T. MATERIALS AND

METHODS:

Specific absorption rate levels during 7T were simulated in Sim4life using infant and adult models. A newly developed acoustic hood was used to guarantee hearing protection. Acoustic noise damping of this hood was measured and compared with the 3T Nordell hood and no hood. In this prospective pilot study, clinically stable infants, between term-equivalent age and the corrected age of 3 months, underwent 7T MR imaging immediately after their standard 3T MR imaging. The 7T scan protocols were developed and optimized while scanning this cohort.

RESULTS:

Global and peak specific absorption rate levels in the infant model in the centered position and 50-mm feet direction did not exceed the levels in the adult model. Hearing protection was guaranteed with the new hood. Twelve infants were scanned. No MR imaging-related adverse events occurred. It was feasible to obtain good-quality imaging at 7T for MRA, MRV, SWI, single-shot T2WI, and MR spectroscopy. T1WI had lower quality at 7T.

CONCLUSIONS:

7T MR imaging is feasible in infants, and good-quality scans could be obtained.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Recém-Nascido / Imageamento por Ressonância Magnética / Lactente Tipo de estudo: Guideline / Observational_studies Limite: Female / Humans / Male Idioma: En Revista: AJNR Am J Neuroradiol Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Recém-Nascido / Imageamento por Ressonância Magnética / Lactente Tipo de estudo: Guideline / Observational_studies Limite: Female / Humans / Male Idioma: En Revista: AJNR Am J Neuroradiol Ano de publicação: 2020 Tipo de documento: Article