Temporal-specific roles of fragile X mental retardation protein in the development of the hindbrain auditory circuit.

Wang, Xiaoyu; Kohl, Ayelet; Yu, Xiaoyan; Zorio, Diego A R; Klar, Avihu; Sela-Donenfeld, Dalit; Wang, Yuan

Wang, Xiaoyu; Kohl, Ayelet; Yu, Xiaoyan; Zorio, Diego A R; Klar, Avihu; Sela-Donenfeld, Dalit; Wang, Yuan.

Afiliação

Wang X; Department of Biomedical Sciences, Program in Neuroscience, Florida State University College of Medicine, Tallahassee, FL 32306, USA.
Kohl A; Division of Histology & Embryology, Key Laboratory for Regenerative Medicine of the Ministry of Education, Medical College, Jinan University, Guangzhou 510632, China.
Yu X; Koret School of Veterinary Medicine, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel.
Zorio DAR; Department of Biomedical Sciences, Program in Neuroscience, Florida State University College of Medicine, Tallahassee, FL 32306, USA.
Klar A; Department of Biomedical Sciences, Program in Neuroscience, Florida State University College of Medicine, Tallahassee, FL 32306, USA.
Sela-Donenfeld D; Department of Medical Neurobiology IMRIC, Hebrew University Medical School, Jerusalem 91120, Israel.
Wang Y; Koret School of Veterinary Medicine, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel yuan.wang@med.fsu.edu dalit.seladon@mail.huji.ac.il.

Development ; 147(21)2020 08 25.

Article em En | MEDLINE | ID: mdl-32747436

Assuntos

Vias Auditivas/embriologia; Vias Auditivas/metabolismo; Proteína do X Frágil da Deficiência Intelectual/metabolismo; Rombencéfalo/embriologia; Rombencéfalo/metabolismo; Animais; Axônios/metabolismo; Sequência de Bases; Sistemas CRISPR-Cas/genética; Embrião de Galinha; Galinhas; Dendritos/metabolismo; Células-Tronco Neurais/metabolismo; Terminações Pré-Sinápticas/metabolismo; RNA Interferente Pequeno/metabolismo; Sinapses/metabolismo; Fatores de Tempo

Palavras-chave

Auditory circuit; Autism spectrum disorder; Axon development; Axon fasciculation; Axon targeting; CRISPR-Cas9; Fragile X syndrome; RNA-binding proteins

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vias Auditivas / Rombencéfalo / Proteína do X Frágil da Deficiência Intelectual Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Development Assunto da revista: BIOLOGIA / EMBRIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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