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Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift.
Knight, Michael J; Woolley, Rachel E; Kwok, Anthony; Parsons, Stuart; Jones, Hannah B L; Gulácsy, Christina E; Phaal, Polly; Kassaar, Omar; Dawkins, Kieran; Rodriguez, Elizabeth; Marques, Andreia; Bowsher, Leo; Wells, Stephen A; Watts, Andrew; van den Elsen, Jean M H; Turner, Alison; O'Hara, John; Pudney, Christopher R.
Afiliação
  • Knight MJ; UCB, 216 Bath Road, Slough SL1 3WE, U.K.
  • Woolley RE; Department of Biology and Biochemistry, University of Bath, Bath, U.K.
  • Kwok A; Department of Biology and Biochemistry, University of Bath, Bath, U.K.
  • Parsons S; Department of Biology and Biochemistry, University of Bath, Bath, U.K.
  • Jones HBL; Department of Biology and Biochemistry, University of Bath, Bath, U.K.
  • Gulácsy CE; Department of Biology and Biochemistry, University of Bath, Bath, U.K.
  • Phaal P; Department of Biology and Biochemistry, University of Bath, Bath, U.K.
  • Kassaar O; Department of Biology and Biochemistry, University of Bath, Bath, U.K.
  • Dawkins K; UCB, 216 Bath Road, Slough SL1 3WE, U.K.
  • Rodriguez E; UCB, 216 Bath Road, Slough SL1 3WE, U.K.
  • Marques A; UCB, 216 Bath Road, Slough SL1 3WE, U.K.
  • Bowsher L; UCB, 216 Bath Road, Slough SL1 3WE, U.K.
  • Wells SA; Department of Physics, University of Bath, Bath, U.K.
  • Watts A; Department of Pharmacy and Pharmacology, University of Bath, Bath, U.K.
  • van den Elsen JMH; Centre for Therapeutic Innovation, University of Bath, Bath, U.K.
  • Turner A; Department of Biology and Biochemistry, University of Bath, Bath, U.K.
  • O'Hara J; Centre for Therapeutic Innovation, University of Bath, Bath, U.K.
  • Pudney CR; UCB, 216 Bath Road, Slough SL1 3WE, U.K.
Biochem J ; 477(18): 3599-3612, 2020 09 30.
Article em En | MEDLINE | ID: mdl-32869839
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais Idioma: En Revista: Biochem J Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Monoclonais Idioma: En Revista: Biochem J Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido