Targeting Cell Cycle in Breast Cancer: CDK4/6 Inhibitors.

Piezzo, Michela; Cocco, Stefania; Caputo, Roberta; Cianniello, Daniela; Gioia, Germira Di; Lauro, Vincenzo Di; Fusco, Giuseppina; Martinelli, Claudia; Nuzzo, Francesco; Pensabene, Matilde; De Laurentiis, Michelino

Piezzo, Michela; Cocco, Stefania; Caputo, Roberta; Cianniello, Daniela; Gioia, Germira Di; Lauro, Vincenzo Di; Fusco, Giuseppina; Martinelli, Claudia; Nuzzo, Francesco; Pensabene, Matilde; De Laurentiis, Michelino.

Afiliação

Piezzo M; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Cocco S; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Caputo R; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Cianniello D; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Gioia GD; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Lauro VD; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Fusco G; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Martinelli C; Department of Clinical Medicine and Surgery, University of Naples "Federico II", 80131 Naples, Italy.
Nuzzo F; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
Pensabene M; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.
De Laurentiis M; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", 80131 Naples, Italy.

Int J Mol Sci ; 21(18)2020 09 04.

Article em En | MEDLINE | ID: mdl-32899866

Assuntos

Quinase 4 Dependente de Ciclina/antagonistas & inibidores; Quinase 6 Dependente de Ciclina/antagonistas & inibidores; Inibidores de Proteínas Quinases/farmacologia; Biomarcadores Farmacológicos/análise; Biomarcadores Farmacológicos/metabolismo; Neoplasias da Mama/tratamento farmacológico; Neoplasias da Mama/metabolismo; Neoplasias da Mama/patologia; Ciclo Celular/efeitos dos fármacos; Ciclo Celular/fisiologia; Quinase 4 Dependente de Ciclina/metabolismo; Quinase 6 Dependente de Ciclina/metabolismo; Piperazinas/farmacologia; Purinas/farmacologia; Piridinas/farmacologia; Receptor ErbB-2/metabolismo; Receptores de Estrogênio/metabolismo

Palavras-chave

CDK4/6 inhibitors; cancer; cell cycle; cyclin-dependent kinase; hormone receptors; hormone therapy; metastatic breast cancer; therapies

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Quinase 4 Dependente de Ciclina / Quinase 6 Dependente de Ciclina Idioma: En Revista: Int J Mol Sci Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália

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