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CSF1R inhibition by a small-molecule inhibitor is not microglia specific; affecting hematopoiesis and the function of macrophages.
Lei, Fengyang; Cui, Naiwen; Zhou, Chengxin; Chodosh, James; Vavvas, Demetrios G; Paschalis, Eleftherios I.
Afiliação
  • Lei F; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114.
  • Cui N; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138.
  • Zhou C; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114.
  • Chodosh J; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114.
  • Vavvas DG; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114.
  • Paschalis EI; Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA 02114; eleftherios_paschalis@meei.harvard.edu.
Proc Natl Acad Sci U S A ; 117(38): 23336-23338, 2020 09 22.
Article em En | MEDLINE | ID: mdl-32900927
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Orgânicos / Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos / Microglia / Hematopoese / Macrófagos Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Orgânicos / Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos / Microglia / Hematopoese / Macrófagos Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article