Toward structure-based drug design against the epidermal growth factor receptor (EGFR).

Haddad, Yazan; Remes, Marek; Adam, Vojtech; Heger, Zbynek

Haddad, Yazan; Remes, Marek; Adam, Vojtech; Heger, Zbynek.

Afiliação

Haddad Y; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-613 00 Brno, Czech Republic; Central European Institute of Technology, Brno University of Technology, Purkynova 656/123, 612 00 Brno, Czech Republic.
Remes M; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-613 00 Brno, Czech Republic; Central European Institute of Technology, Brno University of Technology, Purkynova 656/123, 612 00 Brno, Czech Republic.
Adam V; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-613 00 Brno, Czech Republic; Central European Institute of Technology, Brno University of Technology, Purkynova 656/123, 612 00 Brno, Czech Republic.
Heger Z; Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-613 00 Brno, Czech Republic; Central European Institute of Technology, Brno University of Technology, Purkynova 656/123, 612 00 Brno, Czech Republic. Electronic address: heger@mendelu.cz.

Drug Discov Today ; 26(2): 289-295, 2021 02.

Article em En | MEDLINE | ID: mdl-33075469

Assuntos

Desenho de Fármacos/métodos; Inibidores de Proteínas Quinases/farmacologia; Sítios de Ligação; Tomada de Decisões; Receptores ErbB/antagonistas & inibidores; Receptores ErbB/química; Receptores ErbB/genética; Humanos; Ligantes; Simulação de Acoplamento Molecular; Mutação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Drug Discov Today Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: República Tcheca

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