Successful treatment of invasive aspergillosis caused by Aspergillus parafelis in a kidney transplant recipient.
Med Mycol Case Rep
; 30: 35-38, 2020 Dec.
Article
em En
| MEDLINE
| ID: mdl-33117642
ABSTRACT
Invasive aspergillosis (IA) is associated with a high mortality rate in kidney-transplant recipients. Azole-resistance is increasing in Aspergillus fumigatus. We report a clinical case of a kidney-transplant recipient with cerebellar and pulmonary aspergillosis caused by azole-resistant Aspergillus parafelis (molecular identification through ß-tubulin sequence). The patient experienced an effective resolution after three surgical procedures and associated antifungal therapy. This case highlights that azole-resistant aspergillosis should be considered in every patient with IA as long as susceptibility testing results are not known. Therefore, in selected patients with IA and central nervous system involvement, empirical combination antifungal therapy could be considered.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Med Mycol Case Rep
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Espanha