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LRRC8 family proteins within lysosomes regulate cellular osmoregulation and enhance cell survival to multiple physiological stresses.
Li, Ping; Hu, Meiqin; Wang, Ce; Feng, Xinghua; Zhao, ZhuangZhuang; Yang, Ying; Sahoo, Nirakar; Gu, Mingxue; Yang, Yexin; Xiao, Shiyu; Sah, Rajan; Cover, Timothy L; Chou, Janet; Geha, Raif; Benavides, Fernando; Hume, Richard I; Xu, Haoxing.
Afiliação
  • Li P; Department of Molecular, Cellular, and Developmental Biology, The University of Michigan, Ann Arbor, MI 48109-1085; pinglium@umich.edu rhume@umich.edu.
  • Hu M; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, 310014 Hangzhou, China.
  • Wang C; Department of Molecular, Cellular, and Developmental Biology, The University of Michigan, Ann Arbor, MI 48109-1085.
  • Feng X; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, 310014 Hangzhou, China.
  • Zhao Z; Department of Molecular, Cellular, and Developmental Biology, The University of Michigan, Ann Arbor, MI 48109-1085.
  • Yang Y; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, 310014 Hangzhou, China.
  • Sahoo N; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, 310014 Hangzhou, China.
  • Gu M; Department of Molecular, Cellular, and Developmental Biology, The University of Michigan, Ann Arbor, MI 48109-1085.
  • Yang Y; Department of Molecular, Cellular, and Developmental Biology, The University of Michigan, Ann Arbor, MI 48109-1085.
  • Xiao S; Department of Biology, The University of Texas Rio Grande Valley, Edinburg, TX 78539-2999.
  • Sah R; Department of Molecular, Cellular, and Developmental Biology, The University of Michigan, Ann Arbor, MI 48109-1085.
  • Cover TL; Department of Molecular, Cellular, and Developmental Biology, The University of Michigan, Ann Arbor, MI 48109-1085.
  • Chou J; Department of Molecular, Cellular, and Developmental Biology, The University of Michigan, Ann Arbor, MI 48109-1085.
  • Geha R; Center for Cardiovascular Research, Division of Cardiology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.
  • Benavides F; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37212.
  • Hume RI; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37212.
  • Xu H; Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN 37212.
Proc Natl Acad Sci U S A ; 117(46): 29155-29165, 2020 11 17.
Article em En | MEDLINE | ID: mdl-33139539
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Osmorregulação / Lisossomos / Proteínas de Membrana Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Osmorregulação / Lisossomos / Proteínas de Membrana Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article