Over-expression of ANP32E is associated with poor prognosis of pancreatic cancer and promotes cell proliferation and migration through regulating ß-catenin.

Zhang, Jianwei; Lan, Zhongmin; Qiu, Guotong; Ren, Hu; Zhao, Yajie; Gu, Zongting; Li, Zongze; Feng, Lin; He, Jin; Wang, Chengfeng

Zhang, Jianwei; Lan, Zhongmin; Qiu, Guotong; Ren, Hu; Zhao, Yajie; Gu, Zongting; Li, Zongze; Feng, Lin; He, Jin; Wang, Chengfeng.

Afiliação

Zhang J; Pancreatic and Gastric Surgery Department, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Lan Z; Pancreatic and Gastric Surgery Department, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Qiu G; Pancreatic and Gastric Surgery Department, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Ren H; Pancreatic and Gastric Surgery Department, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Zhao Y; Pancreatic and Gastric Surgery Department, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Gu Z; Pancreatic and Gastric Surgery Department, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Li Z; Pancreatic and Gastric Surgery Department, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Feng L; State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
He J; Department of Surgery, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. jhe11@jhmi.edu.
Wang C; Pancreatic and Gastric Surgery Department, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China. wangchengfeng62@163.com.

BMC Cancer ; 20(1): 1065, 2020 Nov 04.

Article em En | MEDLINE | ID: mdl-33148205

Assuntos

Biomarcadores Tumorais/metabolismo; Regulação Neoplásica da Expressão Gênica; Chaperonas Moleculares/metabolismo; Neoplasias Pancreáticas/patologia; beta Catenina/metabolismo; Apoptose; Biomarcadores Tumorais/genética; Estudos de Casos e Controles; Movimento Celular; Proliferação de Células; Humanos; Chaperonas Moleculares/genética; Neoplasias Pancreáticas/genética; Neoplasias Pancreáticas/metabolismo; Prognóstico; Taxa de Sobrevida; Células Tumorais Cultivadas; Via de Sinalização Wnt; beta Catenina/genética

Palavras-chave

ANP32E; Migration; Pancreatic cancer; Proliferation; ß-Catenin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Chaperonas Moleculares / Beta Catenina Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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