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Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections.
Eapen, Mathew Suji; Lu, Wenying; Hackett, Tillie L; Singhera, Gurpreet Kaur; Thompson, Isobel E; McAlinden, Kielan Darcy; Hardikar, Ashutosh; Weber, Heinrich C; Haug, Greg; Wark, Peter A B; Chia, Collin; Sohal, Sukhwinder Singh.
Afiliação
  • Eapen MS; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Tasmania, Australia.
  • Lu W; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Tasmania, Australia.
  • Hackett TL; Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada.
  • Singhera GK; Department of Medicine, University of British Columbia Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.
  • Thompson IE; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Tasmania, Australia.
  • McAlinden KD; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Tasmania, Australia.
  • Hardikar A; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Tasmania, Australia.
  • Weber HC; Department of Cardiothoracic Surgery, Royal Hobart Hospital, Hobart, Tasmania, Australia.
  • Haug G; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Tasmania, Australia.
  • Wark PAB; Department of Respiratory Medicine, Tasmanian Health Services, North West Hospital, Burnie, Tasmania, Australia.
  • Chia C; Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Tasmania, Australia.
  • Sohal SS; Department of Respiratory Medicine, Launceston General Hospital, Launceston, Tasmania, Australia.
Am J Physiol Lung Cell Mol Physiol ; 320(1): L158-L163, 2021 01 01.
Article em En | MEDLINE | ID: mdl-33174446
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fumar / Vesículas Transportadoras / Doença Pulmonar Obstrutiva Crônica / Enzima de Conversão de Angiotensina 2 / COVID-19 Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Assunto da revista: BIOLOGIA MOLECULAR / FISIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fumar / Vesículas Transportadoras / Doença Pulmonar Obstrutiva Crônica / Enzima de Conversão de Angiotensina 2 / COVID-19 Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Assunto da revista: BIOLOGIA MOLECULAR / FISIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália