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Modular transient nanoclustering of activated ß2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies.
Gormal, Rachel S; Padmanabhan, Pranesh; Kasula, Ravikiran; Bademosi, Adekunle T; Coakley, Sean; Giacomotto, Jean; Blum, Ailisa; Joensuu, Merja; Wallis, Tristan P; Lo, Harriet P; Budnar, Srikanth; Rae, James; Ferguson, Charles; Bastiani, Michele; Thomas, Walter G; Pardon, Els; Steyaert, Jan; Yap, Alpha S; Goodhill, Geoffrey J; Hilliard, Massimo A; Parton, Robert G; Meunier, Frédéric A.
Afiliação
  • Gormal RS; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Padmanabhan P; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Kasula R; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Bademosi AT; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Coakley S; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Giacomotto J; Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Blum A; Queensland Centre for Mental Health Research, West Moreton Hospital and Health Service and University of Queensland, Brisbane, QLD 4072, Australia.
  • Joensuu M; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Wallis TP; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Lo HP; Minerva Foundation Institute for Medical Research, 00290 Helsinki, Finland.
  • Budnar S; Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Rae J; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Ferguson C; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Bastiani M; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Thomas WG; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Pardon E; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Steyaert J; School of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
  • Yap AS; Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels, Belgium.
  • Goodhill GJ; VIB-VUB Center for Structural Biology, VIB, 1050 Brussels, Belgium.
  • Hilliard MA; Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels, Belgium.
  • Parton RG; VIB-VUB Center for Structural Biology, VIB, 1050 Brussels, Belgium.
  • Meunier FA; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Proc Natl Acad Sci U S A ; 117(48): 30476-30487, 2020 12 01.
Article em En | MEDLINE | ID: mdl-33214152
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Conformação Proteica / Modelos Moleculares / Receptores Adrenérgicos beta 2 / Anticorpos de Domínio Único / Imagem Individual de Molécula Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Conformação Proteica / Modelos Moleculares / Receptores Adrenérgicos beta 2 / Anticorpos de Domínio Único / Imagem Individual de Molécula Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália