Decreased mechanotransduction prevents nuclear collapse in a <i>Caenorhabditis elegans</i> laminopathy.

Huelgas-Morales, Gabriela; Sanders, Mark; Mekonnen, Gemechu; Tsukamoto, Tatsuya; Greenstein, David

Decreased mechanotransduction prevents nuclear collapse in a Caenorhabditis elegans laminopathy.

Huelgas-Morales, Gabriela; Sanders, Mark; Mekonnen, Gemechu; Tsukamoto, Tatsuya; Greenstein, David.

Afiliação

Huelgas-Morales G; Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455.
Sanders M; University Imaging Center, University of Minnesota, Minneapolis, MN 55455.
Mekonnen G; Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455.
Tsukamoto T; Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455.
Greenstein D; Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455; green959@umn.edu.

Proc Natl Acad Sci U S A ; 117(49): 31301-31308, 2020 12 08.

Article em En | MEDLINE | ID: mdl-33229589

Assuntos

Caenorhabditis elegans/metabolismo; Núcleo Celular/metabolismo; Laminopatias/patologia; Mecanotransdução Celular; Animais; Proteínas de Caenorhabditis elegans/metabolismo; Interfase; Longevidade; Meiose; Modelos Biológicos; Mutação/genética; Poro Nuclear/metabolismo; Prófase

Palavras-chave

LINC complex; laminopathy; nuclear lamina; nuclear mechanotransduction; torsinA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Núcleo Celular / Caenorhabditis elegans / Mecanotransdução Celular / Laminopatias Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article

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