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Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer.
Tharmalingam, Melissa D; Matilionyte, Gabriele; Wallace, William H B; Stukenborg, Jan-Bernd; Jahnukainen, Kirsi; Oliver, Elizabeth; Goriely, Anne; Lane, Sheila; Guo, Jingtao; Cairns, Bradley; Jorgensen, Anne; Allen, Caroline M; Lopes, Federica; Anderson, Richard A; Spears, Norah; Mitchell, Rod T.
Afiliação
  • Tharmalingam MD; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, Scotland, UK.
  • Matilionyte G; KK Women's and Children's Hospital, Bukit Timah Rd, 100, Singapore, 229899, Singapore.
  • Wallace WHB; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, Scotland, UK.
  • Stukenborg JB; Edinburgh Royal Hospital for Sick Children, 9 Sciennes Road, Edinburgh, EH9 1LF, Scotland, UK.
  • Jahnukainen K; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
  • Oliver E; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
  • Goriely A; Division of Haematology-Oncology and Stem Cell Transplantation, Children's Hospital, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland.
  • Lane S; NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.
  • Guo J; Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX39DS, UK.
  • Cairns B; Department of Paediatrics and Child Health, Oxford University Hospitals NHS Foundation Trust, and Nuffield Department of Womens and Reproductive Health, University of Oxford, Oxford, UK.
  • Jorgensen A; Section of Andrology, Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Allen CM; Howard Hughes Medical Institute, Department of Oncological Sciences and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Lopes F; Howard Hughes Medical Institute, Department of Oncological Sciences and Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT, USA.
  • Anderson RA; Department of Growth and Reproduction, Copenhagen University Hospital (Rigshospitalet), Blegdamsvej 9, 2100, Copenhagen, Denmark.
  • Spears N; Biomedical Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.
  • Mitchell RT; MRC Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, Scotland, UK.
BMC Med ; 18(1): 374, 2020 12 04.
Article em En | MEDLINE | ID: mdl-33272271
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testículo / Carboplatina / Cisplatino / Preservação da Fertilidade / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Child / Humans / Male Idioma: En Revista: BMC Med Assunto da revista: MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testículo / Carboplatina / Cisplatino / Preservação da Fertilidade / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Child / Humans / Male Idioma: En Revista: BMC Med Assunto da revista: MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido