[Research progress of pyroptosis in respiratory diseases].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
; 38(11): 871-874, 2020 Nov 20.
Article
em Zh
| MEDLINE
| ID: mdl-33287489
ABSTRACT
Pyroptosis is a programmed death mode dependent on Caspase-1/4/5/11, which is caused by activation of inflammasome, accompanied by cell membrane rupture, pore formation and cell content release. As a new type of cell death, it is widely involved in respiratory diseases, such as pulmonary fibrosis, acute lung injury, bronchopulmonary dysplasia, chronic obstructive pulmonary disease and asthma. This article reviews the mechanism of pyroptosis and its role in different respiratory diseases, in order to provide new ideas for the treatment of respiratory diseases.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença
/
Piroptose
Limite:
Humans
/
Newborn
Idioma:
Zh
Revista:
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
Assunto da revista:
MEDICINA OCUPACIONAL
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China