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Loss of HER2 and decreased T-DM1 efficacy in HER2 positive advanced breast cancer treated with dual HER2 blockade: the SePHER Study.
Bon, Giulia; Pizzuti, Laura; Laquintana, Valentina; Loria, Rossella; Porru, Manuela; Marchiò, Caterina; Krasniqi, Eriseld; Barba, Maddalena; Maugeri-Saccà, Marcello; Gamucci, Teresa; Berardi, Rossana; Livi, Lorenzo; Ficorella, Corrado; Natoli, Clara; Cortesi, Enrico; Generali, Daniele; La Verde, Nicla; Cassano, Alessandra; Bria, Emilio; Moscetti, Luca; Michelotti, Andrea; Adamo, Vincenzo; Zamagni, Claudio; Tonini, Giuseppe; Barchiesi, Giacomo; Mazzotta, Marco; Marinelli, Daniele; Tomao, Silverio; Marchetti, Paolo; Valerio, Maria Rosaria; Mirabelli, Rosanna; Russo, Antonio; Fabbri, Maria Agnese; D'Ostilio, Nicola; Veltri, Enzo; Corsi, Domenico; Garrone, Ornella; Paris, Ida; Sarobba, Giuseppina; Giotta, Francesco; Garufi, Carlo; Cazzaniga, Marina; Del Medico, Pietro; Roselli, Mario; Sanguineti, Giuseppe; Sperduti, Isabella; Sapino, Anna; De Maria, Ruggero; Leonetti, Carlo; Di Leo, Angelo.
Afiliação
  • Bon G; Cellular Network and Molecular Therapeutic Target Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. giulia.bon@ifo.gov.it.
  • Pizzuti L; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
  • Laquintana V; Pathology Department, IRCCS Regina Elena National CancerInstitute, Rome, Italy.
  • Loria R; Cellular Network and Molecular Therapeutic Target Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
  • Porru M; Area of Translational Research, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Marchiò C; Department of Medical Sciences, University of Turin, Turin, Italy.
  • Krasniqi E; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Turin, Italy.
  • Barba M; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. krasniqier@gmail.com.
  • Maugeri-Saccà M; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
  • Gamucci T; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
  • Berardi R; Medical Oncology, Sandro Pertini Hospital, Rome, Italy.
  • Livi L; Oncology Clinic, "Ospedali Riuniti di Ancona" Hospital, Ancona, Italy.
  • Ficorella C; Radiotherapy Unit, Department of Oncology, Careggi University Hospital, Florence, Italy.
  • Natoli C; Medical Oncology Unit, St Salvatore Hospital, L'Aquila, Italy.
  • Cortesi E; Department of Medical, Oral and Biotechnological Sciences, University Gabriele D'Annunzio, Chieti, Italy.
  • Generali D; Department of Medical Oncology, University La Sapienza, Rome, Italy.
  • La Verde N; Breast Cancer Unit, ASST Cremona, Cremona, Italy.
  • Cassano A; Oncology Unit, ASST Fatebenefratelli Sacco-PO Fatebenefratelli, Milan, Italy.
  • Bria E; Oncology Unit, IRCCS Foundation Polyclinic University A. Gemelli, University Cattolica Del Sacro Cuore, Rome, Italy.
  • Moscetti L; Oncology Unit, IRCCS Foundation Polyclinic University A. Gemelli, University Cattolica Del Sacro Cuore, Rome, Italy.
  • Michelotti A; University of Verona, Verona, Italy.
  • Adamo V; Department of Oncology and Hematology, University Hospital, Modena, Italy.
  • Zamagni C; UO Medical Oncology, S. Chiara Hospital, Pisa, Italy.
  • Tonini G; Medical Oncology Unit, A.O. Papardo & Department of Human Pathology, University of Messina, Messina, Italy.
  • Barchiesi G; Medical Oncology Unit, Addarii Institute of Oncology, S. Orsola-Malpighi Hospital, Bologna, Italy.
  • Mazzotta M; Department of Oncology, University Campus Biomedico, Rome, Italy.
  • Marinelli D; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
  • Tomao S; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
  • Marchetti P; Division of Medical Oncology 2, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
  • Valerio MR; Medical Oncology Unit, Sant'Andrea University Hospital, Rome, Italy.
  • Mirabelli R; Department of Radiological, Oncological and Anatomo-Pathological Sciences, University La Sapienza, Umberto I University Hospital, Rome, Italy.
  • Russo A; Department of Medical Oncology, University La Sapienza, Rome, Italy.
  • Fabbri MA; Medical Oncology Unit, Sant'Andrea University Hospital, Rome, Italy.
  • D'Ostilio N; Medical Oncology, Paolo Giaccone University Hospital, Palermo, Italy.
  • Veltri E; Department of Ematology & Oncology, Pugliese-Ciaccio Hospital, Catanzaro, Italy.
  • Corsi D; Medical Oncology, Paolo Giaccone University Hospital, Palermo, Italy.
  • Garrone O; Medical Oncology Unit, Belcolle Hospital, Viterbo, Italy.
  • Paris I; Medical Oncology Unit, Lanciano-Vasto, Chieti, Italy.
  • Sarobba G; Medical Oncology Unit, Santa Maria Goretti Hospital, Latina, Italy.
  • Giotta F; Medical Oncology Unit, Fatebenefratelli Hospital, Rome, Italy.
  • Garufi C; Medical Oncology AO S. Croce and Carle Teaching Hospital, Cuneo, Italy.
  • Cazzaniga M; Gynaecology - Oncology Unit, University Cattolica del Sacro Cuore, Rome, Italy.
  • Del Medico P; Department of Medical Oncology, ASL Nuro, Nuoro, Italy.
  • Roselli M; Department of Medical Oncology, IRCCS Giovanni Paolo II, Bari, Italy.
  • Sanguineti G; Division of Medical Oncology, Pescara Hospital, Pescara, Italy.
  • Sperduti I; Research Unit Phase I Trials and Oncology Unit, ASST, Monza, Italy.
  • Sapino A; Division of Medical Oncology, Reggio Calabria General Hospital, Reggio Calabria, Italy.
  • De Maria R; Department of Systems Medicine, Medical Oncology, University Tor Vergata, Rome, Italy.
  • Leonetti C; Radiotherapy Department, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Di Leo A; Biostatistics Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
J Exp Clin Cancer Res ; 39(1): 279, 2020 Dec 10.
Article em En | MEDLINE | ID: mdl-33302999
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Protocolos de Quimioterapia Combinada Antineoplásica / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Receptor ErbB-2 Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Protocolos de Quimioterapia Combinada Antineoplásica / Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Receptor ErbB-2 Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália