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1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3ß.
Pomeislová, Alice; Otmar, Miroslav; Rubesová, Petra; Benýsek, Jakub; Matousová, Marika; Mertlíková-Kaiserová, Helena; Pohl, Radek; Postová Slavetínská, Lenka; Pomeisl, Karel; Krecmerová, Marcela.
Afiliação
  • Pomeislová A; Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 43 Prague 2, Czech Republic; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
  • Otmar M; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague 6, Czech Republic.
  • Rubesová P; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
  • Benýsek J; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
  • Matousová M; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
  • Mertlíková-Kaiserová H; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
  • Pohl R; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
  • Postová Slavetínská L; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic.
  • Pomeisl K; Institute of Physics, Czech Academy of Sciences, Na Slovance 1999/2, 182 21 Prague 8, Czech Republic.
  • Krecmerová M; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Flemingovo nám. 2, 166 10 Prague 6, Czech Republic. Electronic address: marcela.krecmerova@uochb.cas.cz.
Bioorg Med Chem ; 32: 115998, 2021 02 15.
Article em En | MEDLINE | ID: mdl-33440320
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiadiazóis / Inibidores Enzimáticos / Catepsina K / Organofosfonatos / Glicogênio Sintase Quinase 3 beta / Antineoplásicos / Nucleosídeos Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: República Tcheca
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiadiazóis / Inibidores Enzimáticos / Catepsina K / Organofosfonatos / Glicogênio Sintase Quinase 3 beta / Antineoplásicos / Nucleosídeos Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: República Tcheca