Fission Yeast Methylenetetrahydrofolate Reductase Ensures Mitotic and Meiotic Chromosome Segregation Fidelity.

Lim, Kim Kiat; Teo, Hwei Yee; Tan, Yuan Yee; Zeng, Yi Bing; Lam, Ulysses Tsz Fung; Choolani, Mahesh; Chen, Ee Sin

Lim, Kim Kiat; Teo, Hwei Yee; Tan, Yuan Yee; Zeng, Yi Bing; Lam, Ulysses Tsz Fung; Choolani, Mahesh; Chen, Ee Sin.

Afiliação

Lim KK; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596, Singapore.
Teo HY; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596, Singapore.
Tan YY; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596, Singapore.
Zeng YB; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596, Singapore.
Lam UTF; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596, Singapore.
Choolani M; National University Health System (NUHS), Singapore 119228, Singapore.
Chen ES; Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.

Int J Mol Sci ; 22(2)2021 Jan 11.

Article em En | MEDLINE | ID: mdl-33440639

Assuntos

Segregação de Cromossomos; Meiose; Metilenotetra-Hidrofolato Redutase (NADPH2)/genética; Metilenotetra-Hidrofolato Redutase (NADPH2)/metabolismo; Mitose; Schizosaccharomyces/enzimologia; Schizosaccharomyces/genética; Alelos; Biomarcadores; Genótipo; Heterocromatina/genética; Heterocromatina/metabolismo; Humanos; Meiose/genética; Mitose/genética; Mutação; Fenótipo

Palavras-chave

MTHFR; Schizosaccharomyces pombe; fission yeast; heterochromatin; meiosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Schizosaccharomyces / Segregação de Cromossomos / Metilenotetra-Hidrofolato Redutase (NADPH2) / Meiose / Mitose Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Singapura

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