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Arg206Cys substitution in DNASE1L3 causes a defect in DNASE1L3 protein secretion that confers risk of systemic lupus erythematosus.
Coke, Latanya N; Wen, Hongxiu; Comeau, Mary; Ghanem, Mustafa H; Shih, Andrew; Metz, Christine N; Li, Wentian; Langefeld, Carl D; Gregersen, Peter K; Simpfendorfer, Kim R.
Afiliação
  • Coke LN; The Institute of Molecular Medicine, Northwell Health Feinstein Institutes for Medical Research, Manhasset, New York, USA.
  • Wen H; The Institute of Molecular Medicine, Northwell Health Feinstein Institutes for Medical Research, Manhasset, New York, USA.
  • Comeau M; Department of Biostatistics and Data Science, Division of Public Health Sciences, School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
  • Ghanem MH; The Institute of Molecular Medicine, Northwell Health Feinstein Institutes for Medical Research, Manhasset, New York, USA.
  • Shih A; Department of Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
  • Metz CN; The Institute of Molecular Medicine, Northwell Health Feinstein Institutes for Medical Research, Manhasset, New York, USA.
  • Li W; The Institute of Molecular Medicine, Northwell Health Feinstein Institutes for Medical Research, Manhasset, New York, USA.
  • Langefeld CD; Department of Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
  • Gregersen PK; The Institute of Molecular Medicine, Northwell Health Feinstein Institutes for Medical Research, Manhasset, New York, USA.
  • Simpfendorfer KR; Department of Biostatistics and Data Science, Division of Public Health Sciences, School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
Ann Rheum Dis ; 80(6): 782-787, 2021 06.
Article em En | MEDLINE | ID: mdl-33455918
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endodesoxirribonucleases / Lúpus Eritematoso Sistêmico Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endodesoxirribonucleases / Lúpus Eritematoso Sistêmico Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos