Evaluation of plan adaptation strategies for stereotactic radiotherapy of lymph node oligometastases using online magnetic resonance image guidance.
Phys Imaging Radiat Oncol
; 9: 58-64, 2019 Jan.
Article
em En
| MEDLINE
| ID: mdl-33458426
ABSTRACT
BACKGROUND AND PURPOSE:
Recent studies have shown that the use of magnetic resonance (MR) guided online plan adaptation yields beneficial dosimetric values and reduces unplanned violations of the dose constraints for stereotactic body radiation therapy (SBRT) of lymph node oligometastases. The purpose of this R-IDEAL stage 0 study was to determine the optimal plan adaptation approach for MR-guided SBRT treatment of lymph node oligometastases. MATERIALS ANDMETHODS:
Using pre-treatment computed tomography (CT) and repeated MR data from five patients with in total 17 pathological lymph nodes, six different methods of plan adaptation were performed on the daily MRI and contours. To determine the optimal plan adaptation approach for treatment of lymph node oligometastases, the adapted plans were evaluated using clinical dose criteria and the time required for performing the plan adaptation.RESULTS:
The average time needed for the different plan adaptation methods ranged between 11 and 119â¯s. More advanced adaptation methods resulted in more plans that met the clinical dose criteria [range, 0-16 out of 17 plans]. The results show a large difference between target coverage achieved by the different plan adaptation methods.CONCLUSION:
Results suggested that multiple plan adaptation methods, based on plan adaptation on the daily anatomy, were feasible for MR-guided SBRT treatment of lymph node oligometastases. The most advanced method, in which a full online replanning was performed by segment shape and weight optimization after fluence optimization, yielded the most favourable dosimetric values and could be performed within a time-frame acceptable (<5â¯min) for MR-guided treatment.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Guideline
Idioma:
En
Revista:
Phys Imaging Radiat Oncol
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Holanda