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Higher interleukin-6 levels and changes in transforming growth factor-ß are associated with lung impairment in pulmonary tuberculosis.
Gupte, Akshay N; Selvaraju, Sriram; Gaikwad, Sanjay; Mave, Vidya; Kumar, Pavan; Babu, Subash; Andrade, Bruno B; Checkley, William; Bollinger, Robert; Gupta, Amita.
Afiliação
  • Gupte AN; Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Selvaraju S; Center for Clinical Global Health Education, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Gaikwad S; Dept of Clinical Research, National Institute for Research in Tuberculosis, Chennai, India.
  • Mave V; Dept of Pulmonary Medicine, Byramjee-Jeejeebhoy Government Medical College, Pune, India.
  • Kumar P; Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Babu S; Center for Clinical Global Health Education, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Andrade BB; National Institutes of Health - National Institute for Research in Tuberculosis - International Center for Excellence in Research, Chennai, India.
  • Checkley W; National Institutes of Health - National Institute for Research in Tuberculosis - International Center for Excellence in Research, Chennai, India.
  • Bollinger R; Instituto Gonçalo Moniz, Fundação Oswaldo Cruz (FIOCRUZ), Salvador, Brazil.
  • Gupta A; Multinational Organisation Network Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Salvador, Brazil.
ERJ Open Res ; 7(1)2021 Jan.
Article em En | MEDLINE | ID: mdl-33532468
ABSTRACT
Higher levels of IL-6 and slow-to-resolve TGF-ß are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. https//bit.ly/2FQEtsz.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: ERJ Open Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: ERJ Open Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos