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Diverse mechanisms activate the PI 3-kinase/mTOR pathway in melanomas: implications for the use of PI 3-kinase inhibitors to overcome resistance to inhibitors of BRAF and MEK.
Tran, Khanh B; Kolekar, Sharada; Jabed, Anower; Jaynes, Patrick; Shih, Jen-Hsing; Wang, Qian; Flanagan, Jack U; Rewcastle, Gordon W; Baguley, Bruce C; Shepherd, Peter R.
Afiliação
  • Tran KB; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.
  • Kolekar S; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Jabed A; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
  • Jaynes P; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.
  • Shih JH; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Wang Q; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Flanagan JU; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Rewcastle GW; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Baguley BC; Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand.
  • Shepherd PR; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
BMC Cancer ; 21(1): 136, 2021 Feb 06.
Article em En | MEDLINE | ID: mdl-33549048
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Resistencia a Medicamentos Antineoplásicos / Fosfatidilinositol 3-Quinase / Serina-Treonina Quinases TOR / Inibidores de Fosfoinositídeo-3 Quinase / Melanoma Limite: Humans Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Nova Zelândia
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Resistencia a Medicamentos Antineoplásicos / Fosfatidilinositol 3-Quinase / Serina-Treonina Quinases TOR / Inibidores de Fosfoinositídeo-3 Quinase / Melanoma Limite: Humans Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Nova Zelândia