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Design, synthesis and biological evaluation of isoxazole-containing biphenyl derivatives as small-molecule inhibitors targeting the programmed cell death-1/ programmed cell death-ligand 1 immune checkpoint.
Zhu, Peiyu; Zhang, Jian; Yang, Yifei; Wang, Lixun; Zhou, Jinpei; Zhang, Huibin.
Afiliação
  • Zhu P; Center of Drug Discovery, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, Nanjing, 210009, People's Republic of China.
  • Zhang J; Center of Drug Discovery, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, Nanjing, 210009, People's Republic of China.
  • Yang Y; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210009, People's Republic of China.
  • Wang L; Center of Drug Discovery, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, Nanjing, 210009, People's Republic of China.
  • Zhou J; Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210009, People's Republic of China. jpzhou668@163.com.
  • Zhang H; Center of Drug Discovery, Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, Nanjing, 210009, People's Republic of China. Zhanghb80@cpu.edu.cn.
Mol Divers ; 26(1): 245-264, 2022 Feb.
Article em En | MEDLINE | ID: mdl-33786726
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígeno B7-H1 / Receptor de Morte Celular Programada 1 Idioma: En Revista: Mol Divers Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígeno B7-H1 / Receptor de Morte Celular Programada 1 Idioma: En Revista: Mol Divers Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article