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In silico screening identifies a novel small molecule inhibitor that counteracts PARP inhibitor resistance in ovarian cancer.
Lin, Z Ping; Al Zouabi, Nour N; Xu, Mark L; Bowen, Nicole E; Wu, Terence L; Lavi, Ethan S; Huang, Pamela H; Zhu, Yong-Lian; Kim, Baek; Ratner, Elena S.
Afiliação
  • Lin ZP; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, 06510, USA. z.ping.lin@yale.edu.
  • Al Zouabi NN; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, 06510, USA.
  • Xu ML; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, 06510, USA.
  • Bowen NE; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Wu TL; Yale West Campus Analytical Core, Yale University, West Haven, CT, 06516, USA.
  • Lavi ES; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, 06510, USA.
  • Huang PH; Department of Pediatrics, Yale University School of Medicine, New Haven, CT, 06510, USA.
  • Zhu YL; Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, 06510, USA.
  • Kim B; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, 30322, USA.
  • Ratner ES; Center for Drug Discovery, Children's Healthcare of Atlanta, Atlanta, GA, 30322, USA.
Sci Rep ; 11(1): 8042, 2021 04 13.
Article em En | MEDLINE | ID: mdl-33850183
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Inibidores de Poli(ADP-Ribose) Polimerases / Carcinoma Epitelial do Ovário Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Inibidores de Poli(ADP-Ribose) Polimerases / Carcinoma Epitelial do Ovário Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos