Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes.

Tindall, Catherine A; Erkner, Estelle; Stichel, Jan; Beck-Sickinger, Annette G; Hoffmann, Anne; Weiner, Juliane; Heiker, John T

Tindall, Catherine A; Erkner, Estelle; Stichel, Jan; Beck-Sickinger, Annette G; Hoffmann, Anne; Weiner, Juliane; Heiker, John T.

Afiliação

Tindall CA; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.
Erkner E; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.
Stichel J; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.
Beck-Sickinger AG; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.
Hoffmann A; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.
Weiner J; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.
Heiker JT; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.

Adipocyte ; 10(1): 216-231, 2021 12.

Article em En | MEDLINE | ID: mdl-33866927

Assuntos

Adipócitos/metabolismo; Peptídeos Penetradores de Células/metabolismo; Adipogenia; Animais; Proliferação de Células; Sobrevivência Celular; Peptídeos Penetradores de Células/análise; Células Cultivadas; Humanos; Lipólise; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Microscopia de Fluorescência

Palavras-chave

Adipose tissue; internalization; kallikrein; obesity; proteolysis; serpin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adipócitos / Peptídeos Penetradores de Células Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Adipocyte Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

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