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Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs.
Saavedra-García, Paula; Roman-Trufero, Monica; Al-Sadah, Hibah A; Blighe, Kevin; López-Jiménez, Elena; Christoforou, Marilena; Penfold, Lucy; Capece, Daria; Xiong, Xiaobei; Miao, Yirun; Parzych, Katarzyna; Caputo, Valentina S; Siskos, Alexandros P; Encheva, Vesela; Liu, Zijing; Thiel, Denise; Kaiser, Martin F; Piazza, Paolo; Chaidos, Aristeidis; Karadimitris, Anastasios; Franzoso, Guido; Snijders, Ambrosius P; Keun, Hector C; Oyarzún, Diego A; Barahona, Mauricio; Auner, Holger W.
Afiliação
  • Saavedra-García P; Cancer Cell Protein Metabolism, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, United Kingdom.
  • Roman-Trufero M; The Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College London, London W12 0NN, United Kingdom.
  • Al-Sadah HA; Cancer Cell Protein Metabolism, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, United Kingdom.
  • Blighe K; The Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College London, London W12 0NN, United Kingdom.
  • López-Jiménez E; Cancer Cell Protein Metabolism, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, United Kingdom.
  • Christoforou M; The Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College London, London W12 0NN, United Kingdom.
  • Penfold L; Clinical Bioinformatics Research, London W1B 3HH, United Kingdom.
  • Capece D; Cancer Cell Protein Metabolism, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, United Kingdom.
  • Xiong X; The Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College London, London W12 0NN, United Kingdom.
  • Miao Y; Cancer Cell Protein Metabolism, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, United Kingdom.
  • Parzych K; The Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College London, London W12 0NN, United Kingdom.
  • Caputo VS; Cancer Cell Protein Metabolism, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, United Kingdom.
  • Siskos AP; Cellular Stress, MRC London Institute of Medical Sciences, London W12 0NN, United Kingdom.
  • Encheva V; Centre for Molecular Immunology and Inflammation, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, United Kingdom.
  • Liu Z; Cancer Cell Protein Metabolism, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, United Kingdom.
  • Thiel D; The Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College London, London W12 0NN, United Kingdom.
  • Kaiser MF; Cancer Cell Protein Metabolism, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, United Kingdom.
  • Piazza P; The Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College London, London W12 0NN, United Kingdom.
  • Chaidos A; Cancer Cell Protein Metabolism, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, United Kingdom.
  • Karadimitris A; The Hugh and Josseline Langmuir Centre for Myeloma Research, Imperial College London, London W12 0NN, United Kingdom.
  • Franzoso G; Department of Surgery and Cancer, Imperial College London, London W12 0NN, United Kingdom.
  • Snijders AP; Proteomics Platform, The Francis Crick Institute, London NW1 1AT, United Kingdom.
  • Keun HC; Department of Mathematics, Imperial College London, London SW7 2AZ, United Kingdom.
  • Oyarzún DA; Department of Brain Sciences, Imperial College London, London W12 0NN, United Kingdom.
  • Barahona M; UK Dementia Research Institute at Imperial College, London W12 0NN, United Kingdom.
  • Auner HW; Department of Mathematics, Imperial College London, London SW7 2AZ, United Kingdom.
Proc Natl Acad Sci U S A ; 118(17)2021 04 27.
Article em En | MEDLINE | ID: mdl-33883278

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido