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A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver.
Inverso, Donato; Shi, Jingjing; Lee, Ki Hong; Jakab, Moritz; Ben-Moshe, Shani; Kulkarni, Shubhada R; Schneider, Martin; Wang, Guanxiong; Komeili, Marziyeh; Vélez, Paula Argos; Riedel, Maria; Spegg, Carleen; Ruppert, Thomas; Schaeffer-Reiss, Christine; Helm, Dominic; Singh, Indrabahadur; Boutros, Michael; Chintharlapalli, Sudhakar; Heikenwalder, Mathias; Itzkovitz, Shalev; Augustin, Hellmut G.
Afiliação
  • Inverso D; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Electronic address: inverso@angioscience.de.
  • Shi J; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Lee KH; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Jakab M; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Ben-Moshe S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Kulkarni SR; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Schneider M; Protein Analysis Unit, Genomics and Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Wang G; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Komeili M; Laboratoire de Spectrométrie de Masse BioOrganique (LSMBO), Université de Strasbourg, CNRS, IPHC UMR 7178, Strasbourg, France.
  • Vélez PA; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
  • Riedel M; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Spegg C; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Ruppert T; Center for Molecular Biology (ZMBH), Heidelberg University, Heidelberg, Germany.
  • Schaeffer-Reiss C; Laboratoire de Spectrométrie de Masse BioOrganique (LSMBO), Université de Strasbourg, CNRS, IPHC UMR 7178, Strasbourg, France.
  • Helm D; Protein Analysis Unit, Genomics and Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Singh I; Emmy Noether Research Group Epigenetic Machineries and Cancer, Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Boutros M; Division of Signaling and Functional Genomics, German Cancer Research Center and Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.
  • Chintharlapalli S; Eli Lilly and Company, Indianapolis, IN, USA.
  • Heikenwalder M; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Itzkovitz S; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Augustin HG; Division of Vascular Oncology and Metastasis Research, German Cancer Research Center (DKFZ), Heidelberg, Germany; European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; German Cancer Consortium, Heidelberg, Germany. Electronic address: augustin@a
Dev Cell ; 56(11): 1677-1693.e10, 2021 06 07.
Article em En | MEDLINE | ID: mdl-34038707
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Transcriptoma / Fígado / Regeneração Hepática Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Dev Cell Assunto da revista: EMBRIOLOGIA Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Transcriptoma / Fígado / Regeneração Hepática Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Dev Cell Assunto da revista: EMBRIOLOGIA Ano de publicação: 2021 Tipo de documento: Article