Differential effect of clopidogrel and ticagrelor on leukocyte count in relation to patient characteristics, biomarkers and genotype: a PLATO substudy.

Nelson, Thomas A; Parker, William A E; Ghukasyan Lakic, Tatevik; Westerbergh, Johan; James, Stefan K; Siegbahn, Agneta; Becker, Richard C; Himmelmann, Anders; Wallentin, Lars; Storey, Robert F

Nelson, Thomas A; Parker, William A E; Ghukasyan Lakic, Tatevik; Westerbergh, Johan; James, Stefan K; Siegbahn, Agneta; Becker, Richard C; Himmelmann, Anders; Wallentin, Lars; Storey, Robert F.

Afiliação

Nelson TA; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
Parker WAE; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
Ghukasyan Lakic T; Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Westerbergh J; Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
James SK; Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Siegbahn A; Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Becker RC; Division of Cardiovascular Health and Disease, Heart, Lung and Vascular Institute, University of Cincinnati College of Medicine, OH, USA.
Himmelmann A; AstraZeneca Research and Development, Gothenburg, Sweden.
Wallentin L; Department of Medical Sciences, Cardiology and Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.
Storey RF; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.

Platelets ; 33(3): 425-431, 2022 Apr 03.

Article em En | MEDLINE | ID: mdl-34077291

Assuntos

Biomarcadores/metabolismo; Clopidogrel/uso terapêutico; Contagem de Leucócitos/métodos; Ticagrelor/uso terapêutico; Clopidogrel/farmacologia; Método Duplo-Cego; Genótipo; Humanos; Fatores de Risco; Ticagrelor/farmacologia

Palavras-chave

acute coronary syndromes; clopidogrel; inflammation; leukocyte; microRNA; ticagrelor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biomarcadores / Clopidogrel / Ticagrelor / Contagem de Leucócitos Tipo de estudo: Clinical_trials / Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Platelets Assunto da revista: HEMATOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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