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Apc-mutant cells act as supercompetitors in intestinal tumour initiation.
van Neerven, Sanne M; de Groot, Nina E; Nijman, Lisanne E; Scicluna, Brendon P; van Driel, Milou S; Lecca, Maria C; Warmerdam, Daniël O; Kakkar, Vaishali; Moreno, Leandro F; Vieira Braga, Felipe A; Sanches, Delano R; Ramesh, Prashanthi; Ten Hoorn, Sanne; Aelvoet, Arthur S; van Boxel, Marouska F; Koens, Lianne; Krawczyk, Przemek M; Koster, Jan; Dekker, Evelien; Medema, Jan Paul; Winton, Douglas J; Bijlsma, Maarten F; Morrissey, Edward; Léveillé, Nicolas; Vermeulen, Louis.
Afiliação
  • van Neerven SM; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • de Groot NE; Oncode Institute, Amsterdam, The Netherlands.
  • Nijman LE; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Scicluna BP; Oncode Institute, Amsterdam, The Netherlands.
  • van Driel MS; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Lecca MC; Oncode Institute, Amsterdam, The Netherlands.
  • Warmerdam DO; Center for Experimental Molecular Medicine, Amsterdam Infection & Immunity, Amsterdam UMC, Amsterdam, The Netherlands.
  • Kakkar V; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam UMC, Amsterdam, The Netherlands.
  • Moreno LF; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Vieira Braga FA; Oncode Institute, Amsterdam, The Netherlands.
  • Sanches DR; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Ramesh P; Oncode Institute, Amsterdam, The Netherlands.
  • Ten Hoorn S; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Aelvoet AS; Oncode Institute, Amsterdam, The Netherlands.
  • van Boxel MF; CRISPR Platform, University of Amsterdam, Cancer Center Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.
  • Koens L; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Krawczyk PM; Oncode Institute, Amsterdam, The Netherlands.
  • Koster J; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Dekker E; Oncode Institute, Amsterdam, The Netherlands.
  • Medema JP; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Winton DJ; Oncode Institute, Amsterdam, The Netherlands.
  • Bijlsma MF; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Morrissey E; Oncode Institute, Amsterdam, The Netherlands.
  • Léveillé N; Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
  • Vermeulen L; Oncode Institute, Amsterdam, The Netherlands.
Nature ; 594(7863): 436-441, 2021 06.
Article em En | MEDLINE | ID: mdl-34079128
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genes APC / Proteína da Polipose Adenomatosa do Colo / Competição entre as Células / Neoplasias Intestinais / Mutação Limite: Animals / Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Genes APC / Proteína da Polipose Adenomatosa do Colo / Competição entre as Células / Neoplasias Intestinais / Mutação Limite: Animals / Female / Humans / Male Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda