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Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function.
Palanikumar, L; Karpauskaite, Laura; Al-Sayegh, Mohamed; Chehade, Ibrahim; Alam, Maheen; Hassan, Sarah; Maity, Debabrata; Ali, Liaqat; Kalmouni, Mona; Hunashal, Yamanappa; Ahmed, Jemil; Houhou, Tatiana; Karapetyan, Shake; Falls, Zackary; Samudrala, Ram; Pasricha, Renu; Esposito, Gennaro; Afzal, Ahmed J; Hamilton, Andrew D; Kumar, Sunil; Magzoub, Mazin.
Afiliação
  • Palanikumar L; Biology Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Karpauskaite L; Biology Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Al-Sayegh M; Biology Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Chehade I; Biology Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Alam M; Department of Biology, SBA School of Science and Engineering, Lahore University of Management Sciences, Lahore, Pakistan.
  • Hassan S; Biology Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Maity D; Department of Chemistry, New York University, New York, NY, USA.
  • Ali L; Core Technology Platforms, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Kalmouni M; Biology Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Hunashal Y; Chemistry Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Ahmed J; DAME, Università di Udine, Udine, Italy.
  • Houhou T; Department of Chemistry and Biochemistry and Knoebel Institute for Healthy Aging, The University of Denver, Denver, CO, USA.
  • Karapetyan S; Biology Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Falls Z; Physics Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Samudrala R; Department of Biomedical Informatics, School of Medicine and Biomedical Sciences, State University of New York (SUNY), Buffalo, NY, USA.
  • Pasricha R; Department of Biomedical Informatics, School of Medicine and Biomedical Sciences, State University of New York (SUNY), Buffalo, NY, USA.
  • Esposito G; Core Technology Platforms, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Afzal AJ; Chemistry Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Hamilton AD; INBB, Rome, Italy.
  • Kumar S; Biology Program, Division of Science, New York University Abu Dhabi, Saadiyat Island Campus, Abu Dhabi, United Arab Emirates.
  • Magzoub M; Department of Chemistry, New York University, New York, NY, USA. andrew.hamilton@nyu.edu.
Nat Commun ; 12(1): 3962, 2021 06 25.
Article em En | MEDLINE | ID: mdl-34172723
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Agregação Patológica de Proteínas / Amiloide / Antineoplásicos Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Emirados Árabes Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Agregação Patológica de Proteínas / Amiloide / Antineoplásicos Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Emirados Árabes Unidos