Protectin conjugates in tissue regeneration 1 restores lipopolysaccharide-induced pulmonary endothelial glycocalyx loss via ALX/SIRT1/NF-kappa B axis.

Wang, Xin-Yang; Li, Xin-Yu; Wu, Cheng-Hua; Hao, Yu; Fu, Pan-Han; Mei, Hong-Xia; Chen, Fang; Gong, Yu-Qiang; Jin, Sheng-Wei; Li, Hui

Wang, Xin-Yang; Li, Xin-Yu; Wu, Cheng-Hua; Hao, Yu; Fu, Pan-Han; Mei, Hong-Xia; Chen, Fang; Gong, Yu-Qiang; Jin, Sheng-Wei; Li, Hui.

Afiliação

Wang XY; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Li XY; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Wu CH; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Hao Y; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Fu PH; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Mei HX; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Chen F; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Gong YQ; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, People's Republic of China.
Jin SW; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, People's Republic of China. jinshengwei69@163.com.
Li H; Department of Anaesthesia and Critical Care, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, 325027, Zhejiang, People's Republic of China. judy198406@sina.com.

Respir Res ; 22(1): 193, 2021 Jul 03.

Article em En | MEDLINE | ID: mdl-34217286

Assuntos

Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Anti-Inflamatórios/farmacologia; Glicocálix/metabolismo; NF-kappa B/metabolismo; Mucosa Respiratória/metabolismo; Sirtuína 1/metabolismo; Proteínas Adaptadoras de Transdução de Sinal/antagonistas & inibidores; Animais; Ácidos Docosa-Hexaenoicos/farmacologia; Glicocálix/efeitos dos fármacos; Células Endoteliais da Veia Umbilical Humana/efeitos dos fármacos; Células Endoteliais da Veia Umbilical Humana/metabolismo; Humanos; Lipopolissacarídeos/toxicidade; Masculino; Camundongos; NF-kappa B/antagonistas & inibidores; Mucosa Respiratória/efeitos dos fármacos; Sirtuína 1/antagonistas & inibidores

Palavras-chave

EXT-1; Glycocalyx; HPA; PCTR1; SIRT1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NF-kappa B / Glicocálix / Mucosa Respiratória / Proteínas Adaptadoras de Transdução de Sinal / Sirtuína 1 / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Respir Res Ano de publicação: 2021 Tipo de documento: Article

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