CpG immunostimulatory oligodeoxynucleotide 1826 as a novel nasal ODN adjuvant enhanced the protective efficacy of the periodontitis gene vaccine in a periodontitis model in SD rats.

Bai, Guohui; Yu, Hang; Guan, Xiaoyan; Zeng, Fengjiao; Liu, Xia; Chen, Bin; Liu, Jianguo; Tian, Yuan

Bai, Guohui; Yu, Hang; Guan, Xiaoyan; Zeng, Fengjiao; Liu, Xia; Chen, Bin; Liu, Jianguo; Tian, Yuan.

Afiliação

Bai G; Key Laboratory of Oral Disease Research, School of Stomatology, Zunyi Medical University, Zunyi, 563000, China.
Yu H; Key Laboratory of Oral Disease Research, School of Stomatology, Zunyi Medical University, Zunyi, 563000, China.
Guan X; Key Laboratory of Oral Disease Research, School of Stomatology, Zunyi Medical University, Zunyi, 563000, China.
Zeng F; Hospital of Stomatology, Zunyi Medical University, Zunyi, 563000, China.
Liu X; Key Laboratory of Oral Disease Research, School of Stomatology, Zunyi Medical University, Zunyi, 563000, China.
Chen B; Hospital of Stomatology, Zunyi Medical University, Zunyi, 563000, China.
Liu J; Key Laboratory of Oral Disease Research, School of Stomatology, Zunyi Medical University, Zunyi, 563000, China.
Tian Y; Key Laboratory of Oral Disease Research, School of Stomatology, Zunyi Medical University, Zunyi, 563000, China.

BMC Oral Health ; 21(1): 403, 2021 08 16.

Article em En | MEDLINE | ID: mdl-34399747

Assuntos

Periodontite; Vacinas; Animais; Imunização; Oligodesoxirribonucleotídeos; Periodontite/prevenção & controle; Porphyromonas gingivalis; Ratos; Ratos Sprague-Dawley

Palavras-chave

Alveolar bone loss; COX-2; CpG-ODN; Periodontitis; Periodontitis gene vaccine; RANKL

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Periodontite / Vacinas Limite: Animals Idioma: En Revista: BMC Oral Health Assunto da revista: ODONTOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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