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Design, synthesis and analysis of novel sphingosine kinase-1 inhibitors to improve oral bioavailability.
Butler, Kendarius J; Castro, Angel A; Dwyer, Tiffany S; Hardwick, Louise M; Iacino, Melody C; Manore, Sara G; Mays, Kevin M; McGlade, Caylie A; Hair, Lisa N; Parker, Erin W; Smith, Mikala R; Turnow, Morgan T; Wilson, Matthew R; Woodson, Stephanie R; Cotham, William E; Walla, Michael D; Hurlbert, Jason C; Christian Grattan, T.
Afiliação
  • Butler KJ; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Castro AA; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Dwyer TS; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Hardwick LM; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Iacino MC; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Manore SG; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Mays KM; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • McGlade CA; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Hair LN; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Parker EW; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Smith MR; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Turnow MT; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Wilson MR; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Woodson SR; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Cotham WE; University of South Carolina, Department of Chemistry and Biochemistry, GSRC Rm 108M, Columbia, SC 29208, United States.
  • Walla MD; University of South Carolina, Department of Chemistry and Biochemistry, GSRC Rm 108M, Columbia, SC 29208, United States.
  • Hurlbert JC; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
  • Christian Grattan T; Winthrop University, Department of Chemistry, Physics and Geology, SIMS Building Rm 101, Rock Hill, SC 29733, United States.
Bioorg Med Chem Lett ; 50: 128329, 2021 10 15.
Article em En | MEDLINE | ID: mdl-34418572

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Proteínas Adaptadoras de Transdução de Sinal / Inibidores Enzimáticos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Proteínas Adaptadoras de Transdução de Sinal / Inibidores Enzimáticos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos