Structural and Genomic Insights Into Pyrazinamide Resistance in <i>Mycobacterium tuberculosis</i> Underlie Differences Between Ancient and Modern Lineages.

Tunstall, Tanushree; Phelan, Jody; Eccleston, Charlotte; Clark, Taane G; Furnham, Nicholas

Structural and Genomic Insights Into Pyrazinamide Resistance in Mycobacterium tuberculosis Underlie Differences Between Ancient and Modern Lineages.

Tunstall, Tanushree; Phelan, Jody; Eccleston, Charlotte; Clark, Taane G; Furnham, Nicholas.

Afiliação

Tunstall T; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Phelan J; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Eccleston C; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Clark TG; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Furnham N; Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.

Front Mol Biosci ; 8: 619403, 2021.

Article em En | MEDLINE | ID: mdl-34422898

Palavras-chave

FoldX; Mycobacterium tuberculosis; biophysical effects; mCSM; non-synonymous Single Nucleotide Polymorphisms; nsSNPs; pncA; thermodynamic stability

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Mol Biosci Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

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