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Optimisation of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity.
Bailey, Brodie L; Nguyen, William; Ngo, Anna; Goodman, Christopher D; Gancheva, Maria R; Favuzza, Paola; Sanz, Laura M; Gamo, Francisco-Javier; Lowes, Kym N; McFadden, Geoffrey I; Wilson, Danny W; Laleu, Benoît; Brand, Stephen; Jackson, Paul F; Cowman, Alan F; Sleebs, Brad E.
Afiliação
  • Bailey BL; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.
  • Nguyen W; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.
  • Ngo A; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia.
  • Goodman CD; School of Biosciences, University of Melbourne, Parkville, Victoria 3010, Australia.
  • Gancheva MR; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia.
  • Favuzza P; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.
  • Sanz LM; Global Health Pharma Research Unit, GlaxoSmithKline, Tres Cantos 28760, Spain.
  • Gamo FJ; Global Health Pharma Research Unit, GlaxoSmithKline, Tres Cantos 28760, Spain.
  • Lowes KN; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.
  • McFadden GI; School of Biosciences, University of Melbourne, Parkville, Victoria 3010, Australia.
  • Wilson DW; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, Australia; Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne 3004, Australia.
  • Laleu B; Medicines for Malaria Venture, Geneva 1215, Switzerland.
  • Brand S; Medicines for Malaria Venture, Geneva 1215, Switzerland.
  • Jackson PF; Global Public Health, Janssen Pharmaceuticals, San Diego, CA, United States.
  • Cowman AF; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia.
  • Sleebs BE; The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville 3010, Australia. Electronic address: sleebs@wehi.edu.au.
Bioorg Chem ; 115: 105244, 2021 10.
Article em En | MEDLINE | ID: mdl-34452759
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Purinas / Plasmodium knowlesi / Eritrócitos / Antimaláricos Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Purinas / Plasmodium knowlesi / Eritrócitos / Antimaláricos Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália